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| 11 |
Barbara Łasut-Szyszka |
Robust Activation of p53 as an Innovative Strategy to Enhance the Sensitivity of Cancer Cells to the FAS Receptor Ligand. |
| 51 |
Noel Ong |
Exploring the Role of Microbiota in Cancer Development in Li-Fraumeni Syndrome. |
| 52 |
Paula Quaglietta |
Metabolic reprogramming in Li-Fraumeni Syndrome underlies the pre-cancer niche and cancer predisposition. |
| 60 |
Risha Banerjee |
p53 coordinates nucleotide metabolism and replication fidelity to enforce chromosomal stability. |
| 59 |
Rentya Moses |
Variation at the R181 residue of p53 confers loss of p53 DNA binding cooperativity with the retention of mitochondrial-associated apoptosis. |
| 61 |
Robert Schwarz |
Mechanisms of p53-mediated transcriptional regulation of transposable elements. |
| 62 |
Ruiying Zhao |
Mutant p53 confers chemoresistance by activating KMT5B-mediated DNA repair pathway in nasopharyngeal carcinoma. |
| 37 |
Lang Zou |
The role of p53 in early primary invasion. |
| 75 |
Sabrina Weber |
MDM2 binds and suppresses RNA polymerase III to restrain the innate immune response to cytosolic DNA. |
| 14 |
Büşra Yüksel |
Structure-Based Rational Design of a High-Affinity DARPin for Reactivating p53 Function. |
| 24 |
Hailey Stack |
Early molecular signatures of TP53 loss of heterozygosity in Li-Fraumeni Syndrome. |
| 63 |
Sasha Blay |
Harnessing Mutational Signatures to Pinpoint the Development of Chemoresistance in Metastatic and Relapsed Osteosarcoma. |
| 64 |
Shunbin Xiong |
Elucidating the p53 transcriptome in the Pancreas for Novel PDAC Therapy. |
| 7 |
Annabella Thomas |
Using fluorescent reporter mice and intravital imaging to investigate the p53 response to oncogene activation driving tumour development. |
| 28 |
Jakov Vuk |
Structural and functional characterization of the p53–β-catenin interactome. |
| 29 |
Juan Pablo Escorcia Domínguez |
Decoding Developmental Vulnerabilities in Sonic Hedgehog Medulloblastoma Tumorigenesis. |
| 30 |
Julianne Funk |
Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations. |
| 67 |
Tanvi Anandampillai |
Exploring the prenatal genetic determinants of tumour risk in Li-Fraumeni syndrome: sequencing of newborn screening dried blood spots. |
| 68 |
Tom Syme |
Design of Pharmacological Chaperones for Mutated p53. |
| 69 |
Václav Brázda |
Promoter G‑Quadruplexes as Structure‑Encoded Switches of p53 Family Activity: Selective Enhancement of Partial‑Function Mutants. |
| 85 |
Susan Kilgas |
A New Layer of p53 Control: The TIRR Pathway. |
| 33 |
Käthe Lehnhoff |
DARPins for recognition and degradation of p53 mutants. |
| 34 |
Katjana Schwab |
Unraveling mechanisms of RFX7 regulation. |
| 36 |
Ksenia Magidey |
EXOp53 – An Extracellular Vesicle Based Platform for Functional p53 Replacement In Vivo. |
| 38 |
Mackenzie Wienke |
Elucidating the mechanism of viral mimicry induction following p53 loss. |
| 39 |
Madeleine Driscoll |
WNT Signaling Variants as Modifiers of TP53-Driven Cancer Susceptibility in Li-Fraumeni Syndrome. |
| 70 |
Vincent Rondeau |
Targeted Prevention as a Novel Approach to Therapy-Related Myeloid Neoplasms. |
| 71 |
Vinod Pant |
Examining the roles of Gtse1 and Eda2r as physiological effectors of p53 activity. |
| 72 |
Wouter Jongeneel |
A mathematical perspective on the robustness of p53 oscillations. |
| 73 |
YiQing Lü |
Functional Annotation of p53 Variants Using in vivo CRISPR Screening and Nurse-Led Clinical Translation. |
| 74 |
Zdenek Andrysik |
Translatome and Proteome Dynamics Modulate the p53 Network. |
| 77 |
Jung-Won Lee |
RUNX3-p53-MYC interplay determines metastatic outgrowth in gastric cancer. |
| 78 |
Meg Dillingham McCullough |
Quantitative single-cell analysis of p53 restoration in TP53-null ovarian cancer cells. |
| 79 |
Airlia Shaffer |
Regulation of p53’s Dual Roles in DNA Repair and Transcription by Time-Dependent Modifications. |
| 80 |
David Miller |
The Origin and Consequences of Heterogeneous p53 Dynamics in Single Cells. |
| 81 |
Sylvain Peuget |
Enterobacteria induce colorectal cancer chemoresistance through stromal-mediated repression of p53. |
| 82 |
Hayla Sluss |
p53 ser 18 regulates post- prandial glucose homeostasis. |
| 83 |
Mahsa Farjami |
Identification of Immunogenic Tumor Antigens for an mRNA-LNP Interception Cancer Vaccine in Li-Fraumeni Syndrome. |
| 87 |
Christopher Cowley |
Identification of inflammation induced epigenetic drivers of colitis-associated colorectal cancer. |
| 88 |
Shuai Allan Huang |
Targeting pro-survival proteins to modulate cell fate following p53 activation. |